|30 September 2010
New Journal Studies
News from ISRS
Joint Meeting News
AAO Online Community
NEW JOURNAL STUDIES
Subconjunctival lidocaine appears to significantly reduce pain from laser retinopexy
This prospective, masked study included 65 patients randomized to subjunctival 2% lidocaine or sham injection before undergoing panretinal photocoagulation or peripheral laser retinopexy. A crossover group of patients who needed a second laser treatment received the opposite injection prior to treatment. Treated patients were more than 20 times more likely to be pain free than patients receiving the sham. In the crossover population, patients were 20 times more likely to prefer the anesthetic over the sham. Ophthalmology, September 2010
Iatrogenic peripheral retinal breaks during vitrectomy more common than previously thought
This retrospective study included 629 patients (645 eyes) – the largest published series -- who underwent 20-gauge pars plana vitrectomy at a single center from 2005 to 2006. Intraoperative iatrogenic peripheral retinal breaks occurred in more than 15 percent of eyes, with wide variation by indication: tractional retinal detachment repair (22.2 percent), macular hole (18.1 percent), dislocated intraocular lens implant (16.7 percent), and epiretinal membrane (13.9 percent). However, the frequency of post-vitrectomy rhegmatogenous retinal detachment was low (1.7 percent). Breaks were most common in the superior retina but also occurred at sites distant to sclerotomies. Ophthalmology, September 2010
Doxycycline may be an effective adjunctive treatment for CNV, pterygium
Researchers tested doxycycline's ability to inhibit ocular-related angiogenesis in three in vivo mouse models: laser-induced choroidal neovascularization (CNV), directed in vivo angiogenesis assay (DIVAA), and pterygium. Doxycycline significantly inhibited angiogenesis in all three models, with the most dramatic effect found in the CNV model followed by the pterygia epithelial cell DIVAA model. The anterior segment pterygium model also showed regression histologically. Though human clinical trials are necessary, the data suggests that doxycycline may prolong the time between VEGF-inhibitor treatment in patients with AMD, and may prevent pterygia recurrence. Ophthalmology, September 2010
Dorzolamide may help treat CME in patients with retinitis pigmentosa, Usher’s syndrome
Researchers evaluated the effect of sustained topical dorzolamide, 2%, on cystic macular lesions in 64 eyes with retinitis pigmentosa or Usher syndrome for six to 58 months. Using OCT imaging, they found central foveal thickness decreased in most cases, while visual acuity improved in more than 30 percent of cases. More than 40 percent of patients showed an improvement in macular cysts in both eyes. Macular cysts worsened in eight patients. Archives of Ophthalmology, September 2010
Clindamycin/dexamethasone combination appears effective for zone 1 toxoplasmic retinochoroiditis
This retrospective review included 12 consecutive patients (12 eyes) who did not tolerate, had contraindications to, or did not respond to oral medications. They received intravitreal injections of clindamycin (1.5 mg/0.1 ml) and dexamethasone (400 μg/0.1 ml) weekly or every four weeks (during pregnancy). All cases resolved after a mean of 3.6 injections and 15.5 days, with no recurrences or complications. After two years there was a significant improvement in central macular thickness and BCVA, with 10 eyes improving by at least two letters. Ophthalmology, September 2010
Study indentifies factors linked to increased rate of visual field loss in glaucoma patients
This prospective, multicentered study included 216 patients with open-angle glaucoma followed up with a standardized protocol for controlling intraocular pressure (targeting a reduction of 30 percent or greater) and then were re-examined every four months. Those with confirmed progression received an additional 20 percent or greater reduction in IOP under the treatment protocol. Patients who were older or had abnormal levels of anticardiolipin antibody had a significantly faster mean visual field change. Modest IOP reduction in these patients significantly ameliorated the rate of visual field decline. Archives of Ophthalmology, September 2010
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NEWS FROM ISRS
Special CXL session at AAO/MEACO Joint Meeting
In the era of worldwide utilization of corneal collagen crosslinking (CXL), how do we define the following: What are keratoconus, FFKC, and suspicious cornea? What is pellucid marginal degeneration? What is ectasia and when it is considered progressive? To answer these and other questions the ISRS will be hosting a special CXL session on Friday, 15 October from 06:30 to 08:00 in Room S403A in McCormick Place during the AAO/MEACO Joint Meeting. The session will be moderated by A. John Kanellopoulos, MD and Theo Seiler, MD, PhD. Contact Dr. Kanellopoulos at firstname.lastname@example.org for inquiries or participation information.
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JOINT MEETING NEWS
Need a Letter of Invitation to come to Chicago next month?
Use the Academy’s online Letter of Invitation generator to create your letter for the 2010 Joint Meeting in Chicago.
Easy Joint Meeting navigation: Yes, there’s an app for that!
Get the Meeting E-Guide’s mobile application today, or during the meeting stop by AAO Connect (booth # 973). The E-Guide contains essential meeting, program and exhibitor information, all of which are conveniently accessible through your SmartPhone or older PDA. Latest web-enabled devices including iPhones, iPads, Android, and WebOS handhelds will see a new look and new features.
A to Z guide to onsite Academy programs and services
Review the Technology Pavilion schedule, find out where the International Center will be located and see what will be exhibited at the Museum of Vision this year. Information about these Academy services and more are listed online for your convenience.
New items added to Orbital Gala silent auction
Join the festivities at the Orbital Gala on Sunday, Oct. 17 at Chicago’s historic Palmer House Hilton. Enjoy dinner, dancing and a silent auction while supporting the Academy Foundation’s educational and public service mission. This year’s auction features unique items including a Lumenis Selecta® II Laser; an Optovue RTVue Optical Coherence Tomography System; a week’s stay on Useppa Island in beautiful Southern Florida; a Silverado Resort spa and golf package in Napa and more. Orbital Gala tickets are still available – purchase by Oct. 8.
Drinks, conversation and…research? Happy hour for young ophthalmologists
Thinking about incorporating research into your career? At the Joint Meeting, stop by the YO ARVO! Young Ophthalmologist Happy Hour – Exploring Careers in Research on Oct. 18, 4 p.m. to 6 p.m., in the YO Lounge (Room N132). Don’t miss this excellent opportunity to chat with established clinician scientists from leading ophthalmic academic institutions. Find more highlights for young ophthalmologists online.
Personalize Academy patient education DVDs at the Joint Meeting
Personalize Academy patient education DVDs with your on-camera introduction in the newly expanded Video Production Studio during the Joint Meeting. Take advantage of this once-a-year opportunity and schedule an appointment today.
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New video on the ONE Network: Pediatric canalicular repair using the pigtail probe
In this video Brian J. Forbes, MD, PhD, demonstrates a hybrid method of repair that uses an eyelet-type pediatric pigtail probe and a self-threading monocanalicular stent. It allows for easier identification and intubation of the proximal injured system, as well as repair without direct suturing of the canaliculus.
Now available: New edition of Basic Ophthalmology
The ninth edition of this concise text provides practical information on the diagnosis, management and referral of common ocular disorders and summarizes important ophthalmic concepts, techniques and facts. It is an ideal complement to the medical student curriculum and is also designed for primary care residents and non-ophthalmic physicians. Updates include neuro-ophthalmology, ocular manifestations of systemic disease, and drugs and the eye. Visit the Academy Store to learn more.
Academy to collect ophthalmic equipment donations for Haiti in Chicago
Since the earthquake, the Academy has been working to assist our colleagues in Haiti in the rebuilding of their practices and the delivery of quality eye care. This year in Chicago, we invite you to bring items to donate - either ophthalmic equipment or current educational books or journals. Ophthalmic equipment must be in good working order. Equipment should be locally serviceable. Educational materials must be current and in good condition. The Academy cannot accept pharmaceuticals. To donate, bring your item(s) to the International Center (Booth 2480, Hall A) at the meeting, along with a completed Haiti Donation Form.
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AAO ONLINE COMMUNITY
What’s new in the Academy online community
Get connected in Chicago: EHR ‘Meet-up’ and other community activities
Electronic health record (EHR) systems have been a hot topic in the community all year. Meet leading contributors to this discussion and discuss your own experiences and challenges. This informal EHR “meet-up” is just one of several community-related activities taking place in Chicago. Find out how you can get connected in Chicago
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